IndiumV2, Main, Exploration, bibRecord, 000C93

In vivo imaging of lymph node migration of MNP- and (111)In-labeled dendritic cells in a transgenic mouse model of breast cancer (MMTV-Ras).

Identifieur interne : 000C93 ( Main/Exploration ); précédent : 000C92; suivant : 000C94

In vivo imaging of lymph node migration of MNP- and (111)In-labeled dendritic cells in a transgenic mouse model of breast cancer (MMTV-Ras).

Auteurs : RBID : pubmed:21598093

English descriptors

KwdEn :
- Animals, Cell Movement, Cell Separation, Cells, Cultured, Dendritic Cells (pathology), Dendritic Cells (radionuclide imaging), Dendritic Cells (ultrastructure), Diagnostic Imaging (methods), Disease Models, Animal, Female, Genes, ras (genetics), Immunohistochemistry, Indium Radioisotopes (diagnostic use), Lymph Nodes (pathology), Lymph Nodes (radionuclide imaging), Magnetic Resonance Imaging, Magnetite Nanoparticles (diagnostic use), Magnetite Nanoparticles (ultrastructure), Mammary Neoplasms, Animal (pathology), Mammary Neoplasms, Animal (radionuclide imaging), Mammary Tumor Virus, Mouse (metabolism), Mice, Mice, Transgenic, Phenotype, Staining and Labeling, Tomography, Emission-Computed, Single-Photon.
MESH :
- chemical , diagnostic use : Indium Radioisotopes, Magnetite Nanoparticles.
- genetics : Genes, ras.
- metabolism : Mammary Tumor Virus, Mouse.
- methods : Diagnostic Imaging.
- pathology : Dendritic Cells, Lymph Nodes, Mammary Neoplasms, Animal.
- radionuclide imaging : Dendritic Cells, Lymph Nodes, Mammary Neoplasms, Animal.
- ultrastructure : Dendritic Cells, Magnetite Nanoparticles.
- Animals, Cell Movement, Cell Separation, Cells, Cultured, Disease Models, Animal, Female, Immunohistochemistry, Magnetic Resonance Imaging, Mice, Mice, Transgenic, Phenotype, Staining and Labeling, Tomography, Emission-Computed, Single-Photon.

Abstract

The authors present a protocol for the in vivo evaluation, using different imaging techniques, of lymph node (LN) homing of tumor-specific dendritic cells (DCs) in a murine breast cancer model.

DOI: 10.1007/s11307-011-0496-0
PubMed: 21598093

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 001373
to stream Main, to step Curation: 001373

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">In vivo imaging of lymph node migration of MNP- and (111)In-labeled dendritic cells in a transgenic mouse model of breast cancer (MMTV-Ras).</title>
<author><name sortKey="Martelli, Cristina" uniqKey="Martelli C">Cristina Martelli</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Biomedical Sciences and Technologies, Section of Radiological Sciences, University of Milan, via di Rudinì 8, 20142 Milan, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Biomedical Sciences and Technologies, Section of Radiological Sciences, University of Milan, via di Rudinì 8, 20142 Milan</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Borelli, Manuela" uniqKey="Borelli M">Manuela Borelli</name>
</author>
<author><name sortKey="Ottobrini, Luisa" uniqKey="Ottobrini L">Luisa Ottobrini</name>
</author>
<author><name sortKey="Rainone, Veronica" uniqKey="Rainone V">Veronica Rainone</name>
</author>
<author><name sortKey="Degrassi, Anna" uniqKey="Degrassi A">Anna Degrassi</name>
</author>
<author><name sortKey="Russo, Micaela" uniqKey="Russo M">Micaela Russo</name>
</author>
<author><name sortKey="Gianelli, Umberto" uniqKey="Gianelli U">Umberto Gianelli</name>
</author>
<author><name sortKey="Bosari, Silvano" uniqKey="Bosari S">Silvano Bosari</name>
</author>
<author><name sortKey="Fiorini, Carlo" uniqKey="Fiorini C">Carlo Fiorini</name>
</author>
<author><name sortKey="Trabattoni, Daria" uniqKey="Trabattoni D">Daria Trabattoni</name>
</author>
<author><name sortKey="Clerici, Mario" uniqKey="Clerici M">Mario Clerici</name>
</author>
<author><name sortKey="Lucignani, Giovanni" uniqKey="Lucignani G">Giovanni Lucignani</name>
</author>
</titleStmt>
<publicationStmt><date when="2012">2012</date>
<idno type="doi">10.1007/s11307-011-0496-0</idno>
<idno type="RBID">pubmed:21598093</idno>
<idno type="pmid">21598093</idno>
<idno type="wicri:Area/Main/Corpus">001373</idno>
<idno type="wicri:Area/Main/Curation">001373</idno>
<idno type="wicri:Area/Main/Exploration">000C93</idno>
</publicationStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Cell Movement</term>
<term>Cell Separation</term>
<term>Cells, Cultured</term>
<term>Dendritic Cells (pathology)</term>
<term>Dendritic Cells (radionuclide imaging)</term>
<term>Dendritic Cells (ultrastructure)</term>
<term>Diagnostic Imaging (methods)</term>
<term>Disease Models, Animal</term>
<term>Female</term>
<term>Genes, ras (genetics)</term>
<term>Immunohistochemistry</term>
<term>Indium Radioisotopes (diagnostic use)</term>
<term>Lymph Nodes (pathology)</term>
<term>Lymph Nodes (radionuclide imaging)</term>
<term>Magnetic Resonance Imaging</term>
<term>Magnetite Nanoparticles (diagnostic use)</term>
<term>Magnetite Nanoparticles (ultrastructure)</term>
<term>Mammary Neoplasms, Animal (pathology)</term>
<term>Mammary Neoplasms, Animal (radionuclide imaging)</term>
<term>Mammary Tumor Virus, Mouse (metabolism)</term>
<term>Mice</term>
<term>Mice, Transgenic</term>
<term>Phenotype</term>
<term>Staining and Labeling</term>
<term>Tomography, Emission-Computed, Single-Photon</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="diagnostic use" xml:lang="en"><term>Indium Radioisotopes</term>
<term>Magnetite Nanoparticles</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Genes, ras</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Mammary Tumor Virus, Mouse</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Diagnostic Imaging</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Dendritic Cells</term>
<term>Lymph Nodes</term>
<term>Mammary Neoplasms, Animal</term>
</keywords>
<keywords scheme="MESH" qualifier="radionuclide imaging" xml:lang="en"><term>Dendritic Cells</term>
<term>Lymph Nodes</term>
<term>Mammary Neoplasms, Animal</term>
</keywords>
<keywords scheme="MESH" qualifier="ultrastructure" xml:lang="en"><term>Dendritic Cells</term>
<term>Magnetite Nanoparticles</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Cell Movement</term>
<term>Cell Separation</term>
<term>Cells, Cultured</term>
<term>Disease Models, Animal</term>
<term>Female</term>
<term>Immunohistochemistry</term>
<term>Magnetic Resonance Imaging</term>
<term>Mice</term>
<term>Mice, Transgenic</term>
<term>Phenotype</term>
<term>Staining and Labeling</term>
<term>Tomography, Emission-Computed, Single-Photon</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The authors present a protocol for the in vivo evaluation, using different imaging techniques, of lymph node (LN) homing of tumor-specific dendritic cells (DCs) in a murine breast cancer model.</div>
</front>
</TEI>
<pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">21598093</PMID>
<DateCreated><Year>2012</Year>
<Month>03</Month>
<Day>08</Day>
</DateCreated>
<DateCompleted><Year>2012</Year>
<Month>09</Month>
<Day>27</Day>
</DateCompleted>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1860-2002</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>14</Volume>
<Issue>2</Issue>
<PubDate><Year>2012</Year>
<Month>Apr</Month>
</PubDate>
</JournalIssue>
<Title>Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging</Title>
<ISOAbbreviation>Mol Imaging Biol</ISOAbbreviation>
</Journal>
<ArticleTitle>In vivo imaging of lymph node migration of MNP- and (111)In-labeled dendritic cells in a transgenic mouse model of breast cancer (MMTV-Ras).</ArticleTitle>
<Pagination><MedlinePgn>183-96</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1007/s11307-011-0496-0</ELocationID>
<Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">The authors present a protocol for the in vivo evaluation, using different imaging techniques, of lymph node (LN) homing of tumor-specific dendritic cells (DCs) in a murine breast cancer model.</AbstractText>
<AbstractText Label="PROCEDURES" NlmCategory="METHODS">Bone marrow DCs were labeled with paramagnetic nanoparticles (MNPs) or (111)In-oxine. Antigen loading was performed using tumor lysate. Mature DCs were injected into the footpads of transgenic tumor-bearing mice (MMTV-Ras) and DC migration was tracked by magnetic resonance imaging (MRI) and single-photon emission computed tomography (SPECT). Ex vivo analyses were performed to validate the imaging data.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">DC labeling, both with MNPs and with (111)In-oxine, did not affect DC phenotype or functionality. MRI and SPECT allowed the detection of iron and (111)In in both axillary and popliteal LNs. Immunohistochemistry and γ-counting revealed the presence of DCs in LNs.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">MRI and SPECT imaging, by allowing in vivo dynamic monitoring of DC migration, could further the development and optimization of efficient anti-cancer vaccines.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Martelli</LastName>
<ForeName>Cristina</ForeName>
<Initials>C</Initials>
<Affiliation>Department of Biomedical Sciences and Technologies, Section of Radiological Sciences, University of Milan, via di Rudinì 8, 20142 Milan, Italy.</Affiliation>
</Author>
<Author ValidYN="Y"><LastName>Borelli</LastName>
<ForeName>Manuela</ForeName>
<Initials>M</Initials>
</Author>
<Author ValidYN="Y"><LastName>Ottobrini</LastName>
<ForeName>Luisa</ForeName>
<Initials>L</Initials>
</Author>
<Author ValidYN="Y"><LastName>Rainone</LastName>
<ForeName>Veronica</ForeName>
<Initials>V</Initials>
</Author>
<Author ValidYN="Y"><LastName>Degrassi</LastName>
<ForeName>Anna</ForeName>
<Initials>A</Initials>
</Author>
<Author ValidYN="Y"><LastName>Russo</LastName>
<ForeName>Micaela</ForeName>
<Initials>M</Initials>
</Author>
<Author ValidYN="Y"><LastName>Gianelli</LastName>
<ForeName>Umberto</ForeName>
<Initials>U</Initials>
</Author>
<Author ValidYN="Y"><LastName>Bosari</LastName>
<ForeName>Silvano</ForeName>
<Initials>S</Initials>
</Author>
<Author ValidYN="Y"><LastName>Fiorini</LastName>
<ForeName>Carlo</ForeName>
<Initials>C</Initials>
</Author>
<Author ValidYN="Y"><LastName>Trabattoni</LastName>
<ForeName>Daria</ForeName>
<Initials>D</Initials>
</Author>
<Author ValidYN="Y"><LastName>Clerici</LastName>
<ForeName>Mario</ForeName>
<Initials>M</Initials>
</Author>
<Author ValidYN="Y"><LastName>Lucignani</LastName>
<ForeName>Giovanni</ForeName>
<Initials>G</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType>Journal Article</PublicationType>
<PublicationType>Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Mol Imaging Biol</MedlineTA>
<NlmUniqueID>101125610</NlmUniqueID>
<ISSNLinking>1536-1632</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance>Indium Radioisotopes</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance>Magnetite Nanoparticles</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="Y">Cell Movement</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Cell Separation</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Cells, Cultured</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Dendritic Cells</DescriptorName>
<QualifierName MajorTopicYN="Y">pathology</QualifierName>
<QualifierName MajorTopicYN="N">radionuclide imaging</QualifierName>
<QualifierName MajorTopicYN="N">ultrastructure</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Diagnostic Imaging</DescriptorName>
<QualifierName MajorTopicYN="Y">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Disease Models, Animal</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Genes, ras</DescriptorName>
<QualifierName MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Immunohistochemistry</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Indium Radioisotopes</DescriptorName>
<QualifierName MajorTopicYN="Y">diagnostic use</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Lymph Nodes</DescriptorName>
<QualifierName MajorTopicYN="N">pathology</QualifierName>
<QualifierName MajorTopicYN="Y">radionuclide imaging</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Magnetic Resonance Imaging</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Magnetite Nanoparticles</DescriptorName>
<QualifierName MajorTopicYN="Y">diagnostic use</QualifierName>
<QualifierName MajorTopicYN="N">ultrastructure</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Mammary Neoplasms, Animal</DescriptorName>
<QualifierName MajorTopicYN="N">pathology</QualifierName>
<QualifierName MajorTopicYN="Y">radionuclide imaging</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Mammary Tumor Virus, Mouse</DescriptorName>
<QualifierName MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Mice</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Mice, Transgenic</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Phenotype</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Staining and Labeling</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Tomography, Emission-Computed, Single-Photon</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2011</Year>
<Month>5</Month>
<Day>21</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2011</Year>
<Month>5</Month>
<Day>21</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2012</Year>
<Month>9</Month>
<Day>28</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="doi">10.1007/s11307-011-0496-0</ArticleId>
<ArticleId IdType="pubmed">21598093</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=IndiumV2/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000C93 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000C93 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=   *** parameter Area/wikiCode missing *** 
   |area=    IndiumV2
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:21598093
   |texte=   In vivo imaging of lymph node migration of MNP- and (111)In-labeled dendritic cells in a transgenic mouse model of breast cancer (MMTV-Ras).
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:21598093" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a IndiumV2

This area was generated with Dilib version V0.5.76.
Data generation: Tue May 20 07:24:43 2014. Site generation: Thu Mar 7 11:12:53 2024

	Serveur d'exploration sur l'Indium
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur l'Indium

In vivo imaging of lymph node migration of MNP- and (111)In-labeled dendritic cells in a transgenic mouse model of breast cancer (MMTV-Ras).

In vivo imaging of lymph node migration of MNP- and (111)In-labeled dendritic cells in a transgenic mouse model of breast cancer (MMTV-Ras).

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki